Jerusha Kali, on the eve of University graduation and her 21st birthday - has her genetic mutation kick in; this enables her to emit an abnormal electromagnetic field; stemming from her pineal gland, which is extremely powerful. She is able to manipulate space and time, and travel inter-dimensionally. She is the last surviving Witch. All of her ancestors have been successfully eradicated by an elite Secret Society which controls much of the various institutions of the world. This Secret Society is evil, ancient and has technological innovation on their side. She incorporates Allies of various relict secret societies; mostly of Nordic and Indigenous origins and inevitably has to do battle with the formidable foes before the eve of her 21st Birthday - which is the Full Moon - where her powers will fully culminate. It is prophesized that she is the one to lead the global revolution to return planet earth to homeostasis.
Office misfit Darlene Henderson, AKA "Kitty", takes her cat obsession to perverted and supernatural places, dragging her hapless co-workers John and Janine down dark and feral alleyways of murder and lust.
Vincent Pepe who wanted to be a powerful leader of a righteous gang that ruled the city, like his seniors. And then there's the rival clan with the malicious gangsters of Angamaly a locale on which the film is based.
Six therapy patients are brought together at a secluded cabin to confront their strangest fears. But these fears won't just hurt them...they will kill them.